Arsene Wenger has predominantly used the competition to showcase the talent of youngsters, but has gone for a bit of experience with the two aforementioned players.
The Gunners have made eight changes to the team that beat Crystal Palace.
Santi Cazorla and Laurent Koscielny have kept their place, while Nicklas Bendtner starts up front.
Chelsea have made 10 changes to the side that beat Manchester City.
Juan Mata, David Luiz, Willian, Michael Essien and Samuel Eto'o will all start at the Emirates.
Arsenal team: Fabianski, Jenkinson, Vermaelen, Koscielny, Monreal, Ramsey, Wilshere, Rosicky, Cazorla, Ryo, Bendtner
Subs: Viviano, Sagna, Hayden, Yennaris, Ozil, Giroud, Park
Chelsea team: Schwarzer; Azpilicueta, Cahill, D Luiz, Bertrand; Essien (c), Mikel, De Bruyne, Mata, Willian, Eto'o.
Subs: Blackman, Ivanovic, Kalas, Ramires, Hazard, Torres, Ba
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